A novel organ culture model of aorta for vascular calcification
نویسندگان
چکیده
منابع مشابه
A novel organ culture model of aorta for vascular calcification.
Vascular calcification is a characteristic feature of aging, atherosclerosis, diabetes mellitus, and end-stage renal disease. The use of organ culture provides complementary information that may bridge the gap between traditional cell culture and animal models, and establishes easily controlled experimental conditions. Therefore, we investigated whether organ culture of the aorta could be used ...
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Vascular calcification increasingly afflicts our aging and dysmetabolic population. Once considered a passive process, it has emerged as an actively regulated form of calcified tissue metabolism, resembling the mineralization of endochondral and membranous bone. Executive cell types familiar to bone biologists, osteoblasts, chondrocytes, and osteoclasts, are seen in calcifying macrovascular spe...
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ژورنال
عنوان ژورنال: Atherosclerosis
سال: 2016
ISSN: 0021-9150
DOI: 10.1016/j.atherosclerosis.2015.11.005